aggravation

noun

1. an exasperated feeling of annoyance

   noun.feeling

   Synonyms exasperation

   Source: WordNet 3.0

2. unfriendly behavior that causes anger or resentment

   noun.act

   Synonyms irritation provocation

   Source: WordNet 3.0

3. action that makes a problem or a disease (or its symptoms) worse

   noun.act

   Examples

   The aggravation of her condition resulted from lack of care.

   Synonyms exacerbation

   Source: WordNet 3.0

4. The act of aggravating, or making worse; -- used of evils, natural or moral; the act of increasing in severity or heinousness; something additional to a crime or wrong and enhancing its guilt or injurious consequences.

   noun

   Source: webster1913